It could be argued that there is no more famous Goddess in modern Paganism than Isis. Her figure -- often winged, with ankh in hand or perhaps an infant Horus, usually crowned by a sun and horns -- is immediately recognizable.
Such was the case in much of the ancient Western world, as well. Known as Au Set or Aset in Egypt, her myths and worship spread across northern Africa, deep into the Middle East, throughout Europe, and as far north as Roman Britain. The memory of her survived even into the Christian Middle Ages. With the (re)birth of Paganism, songs and hymns are once again being raised in her honor; Wiccans, solitary Pagans, Goddess Spiritualists, Kemetics and many others praise her as the Queen of Heaven, the Throne of Creation, the Great Magician, the Mother of Mothers, the Rose of Eternal Life.
Isis was the first non-Greek Goddess to catch my eye. I loved reading stories about her: how she won the Secret Name of Ra, how she mourned her murdered husband, conceived a son, and eventually helped him to win his rightful throne. I found it fascinating that Isis was the personification of the Egyptian throne and that the few women to rule Egypt in their own name (such as Cleopatra VII) closely identified with her.